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Gene : ARFGEF2 Homo sapiens

Name  ? ADP ribosylation factor guanine nucleotide exchange factor 2 Cytological Location  20q13.13
Brief Description  ADP ribosylation factor guanine nucleotide exchange factor 2
description  ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq, Jul 2008]
  • synonyms:
  • Brefeldin A-inhibited guanine nucleotide-exchange protein 2,
  • ARFGEF2,
  • BIG2,
  • ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited),
  • dJ1164I10.1,
  • BIG2,
  • PVNH2,
  • HGNC:15853,
  • uc002xtx.5,
  • AF084521,
  • OTTHUMG00000032687,
  • NM_006420
  • identifiers:
  • 10564,
  • ENSG00000124198,
  • ARFGEF2

Genome feature

Region: gene ? Length: 114973  
Location: 20:48921721-49036693 Cyto location: 20q13.13


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Disease

1 Diseases

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772 SN Ps

5 Cross References

19 Data Sets

22 Homologues

0 Located Features

90 Rna Seq Results