help  | about  | cite  | software

Gene : LOC106799842 Homo sapiens

Name  ? nonconserved acetylation island sequence 101 enhancer Cytological Location  6p21.3
description  This region, which is poorly conserved between human and mouse at the sequence level, can function as an enhancer in human Jurkat T cells. It is located in the major histocompatibility complex (MHC) region of chromosome 6, with several haplotypes of this region represented in the GRCh38 reference genome assembly. The chromatin structure of this region represents a histone acetylation island in human T cells based on the diacetylation of histone H3 at lysines 9 and 14. An adjacent overlapping sequence was also validated as a functional enhancer by high-throughput massively parallel reporter assays (MPRAs) in both liver carcinoma HepG2 cells and erythroleukemia K562 cells. That enhancer region contains a motif for the NFE2L2 activator, and mutation of the motif results in reduced enhancer activity. [provided by RefSeq, Nov 2017]
  • identifiers:
  • 106799842,
  • LOC106799842

Genome feature

Region: gene ?
Location: No location information in HumanMine Cyto location: 6p21.3


Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Gene --> Orthologues

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

0 Pathways

0 SN Ps

1 Cross References

3 Data Sets

0 Homologues

0 Located Features

0 Rna Seq Results