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Gene : LOC107648856 Homo sapiens

Name  ? meiotic recombination hotspot DMB1 Cytological Location  6p21.3
description  This region partially overlaps the major histocompatibility complex, class II, DM beta (HLA-DMB) gene on the p arm of chromosome 6. This region has been identified as a meiotic recombination hotspot by sperm typing assays and linkage disequilibrium studies, and another meiotic recombination hotspot has been identified just upstream of this region relative to the reference genome. HapMap data shows an increased recombination rate in the region. Higher recombination frequencies in females relative to males has been reported in the MHC class II region. Meiotic hotspot activity can vary widely amongst individuals and can be influenced by both the nucleotide sequence at the meiotic recombination hotspot and the specific alleles present at the PR domain 9 (PRDM9) locus. This region has weak meiotic recombination hotspot activity in the males examined in some populations. [provided by RefSeq, Oct 2016]
  • identifiers:
  • 107648856,
  • LOC107648856

Genome feature

Region: gene ?
Location: No location information in HumanMine Cyto location: 6p21.3


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Disease

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Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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1 Cross References

3 Data Sets

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