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Gene : LOC107648864 Homo sapiens

Name  ? meiotic recombination hotspot DNA2 Cytological Location  6p21.3
description  This region lies within the 3' untranslated region (UTR) of the major histocompatibility complex, class II, DO alpha (HLA-DOA) gene on the p arm of chromosome 6. This region has been identified as a meiotic recombination hotspot by sperm typing assays and linkage disequilibrium studies, but has been shown to have a lower recombination frequency than the DNA3 meiotic recombination hotspot located upstream of this region relative to the reference genome. Two meiotic recombination hotspots have been identified near this region, the DNA1 and DNA3 meiotic recombination hotspots, located downstream and upstream of this region relative to the reference genome, respectively. Higher recombination frequencies in females relative to males has been reported in the MHC class II region. Meiotic hotspot activity can vary widely amongst individuals and can be influenced by both the nucleotide sequence at the meiotic recombination hotspot and the specific alleles present at the PR domain 9 (PRDM9) locus. [provided by RefSeq, Apr 2016]
  • identifiers:
  • 107648864,
  • LOC107648864

Genome feature

Region: gene ?
Location: No location information in HumanMine Cyto location: 6p21.3

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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0 Pathways

0 SN Ps

1 Cross References

3 Data Sets

0 Homologues

0 Located Features

0 Rna Seq Results