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Gene : ALDH1L1 Homo sapiens

Name  ? aldehyde dehydrogenase 1 family member L1 Cytological Location  3q21.3
Brief Description  aldehyde dehydrogenase 1 family member L1
description  The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
  • synonyms:
  • OTTHUMG00000125551,
  • NM_012190,
  • FDH,
  • 10-FTHFDH,
  • FTHFD,
  • 10-fTHF,
  • uc003eim.3,
  • cytosolic 10-formyltetrahydrofolate dehydrogenase,
  • FDH,
  • formyltetrahydrofolate dehydrogenase,
  • 10-fTHF,
  • FTHFD,
  • AF052732,
  • aldehyde dehydrogenase 1 family, member L1,
  • HGNC:3978,
  • ALDH1L1
  • identifiers:
  • 10840,
  • ENSG00000144908,
  • ALDH1L1

Genome feature

Region: gene ? Length: 94198  
Location: 3:126103561-126197758 reverse strand Cyto location: 3q21.3


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Proteins

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SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

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Other

340 SN Ps

5 Cross References

17 Data Sets

16 Homologues

0 Located Features

90 Rna Seq Results