help  | about  | cite  | software

Gene : PPARGC1A Homo sapiens

Name  ? PPARG coactivator 1 alpha Cytological Location  4p15.2
Brief Description  PPARG coactivator 1 alpha
description  The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. [provided by RefSeq, Jul 2008]
  • synonyms:
  • PGC1,
  • PGC1A,
  • PGC-1v,
  • uc003gqs.3,
  • AF106698,
  • HGNC:9237,
  • PPARGC1A,
  • PGC-1alpha,
  • NM_013261,
  • PGC1,
  • PGC1A,
  • PGC-1alpha,
  • peroxisome proliferative activated receptor, gamma, coactivator 1,
  • OTTHUMG00000097747,
  • LEM6,
  • PPARGC1,
  • PPARGC1,
  • PPARgamma coactivator 1alpha,
  • peroxisome proliferator-activated receptor gamma, coactivator 1 alpha,
  • PGC-1(alpha),
  • peroxisome proliferative activated receptor, gamma, coactivator 1, alpha
  • identifiers:
  • 10891,
  • ENSG00000109819,
  • PPARGC1A

Genome feature

Region: gene ? Length: 680809  
Location: 4:23792021-24472829 reverse strand Cyto location: 4p15.2


Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

Gene --> GO terms.

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Gene --> Orthologues

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

131 SN Ps

5 Cross References

16 Data Sets

6 Homologues

11 Located Features

90 Rna Seq Results