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Gene : TLK2 Homo sapiens

Name  ? tousled like kinase 2 Cytological Location  17q23.2
Brief Description  tousled like kinase 2
description  This gene encodes a nuclear serine/threonine kinase that was first identified in Arabidopsis. The encoded protein is thought to function in the regulation of chromatin assembly in the S phase of the cell cycle by regulating the levels of a histone H3/H4 chaperone. This protein is associated with double-strand break repair of DNA damage caused by radiation. Pseudogenes of this gene are present on chromosomes 10 and 17. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
  • synonyms:
  • AB004884,
  • HsHPK,
  • OTTHUMG00000179176,
  • TLK2,
  • MRD57,
  • MGC44450,
  • HGNC:11842,
  • tousled-like kinase 2,
  • uc002izz.5,
  • NM_006852,
  • identifiers:
  • 11011,
  • ENSG00000146872,
  • TLK2

Genome feature

Region: gene ? Length: 144574  
Location: 17:62470908-62615481 Cyto location: 17q23.2

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Orthologues


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

23 SN Ps

5 Cross References

16 Data Sets

7 Homologues

0 Located Features

90 Rna Seq Results