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Gene : AKR1C4 Homo sapiens

Name  ? aldo-keto reductase family 1 member C4 Cytological Location  10p15.1
Brief Description  aldo-keto reductase family 1 member C4
description  This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008]
  • synonyms:
  • chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4,
  • CHDR,
  • CHDR,
  • DD4,
  • OTTHUMG00000017591,
  • MGC22581,
  • CDR,
  • DD-4,
  • aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4),
  • 3-alpha-HSD,
  • C11,
  • uc057rjf.1,
  • 3-alpha-HSD,
  • HAKRA,
  • CDR,
  • HGNC:387,
  • AKR1C4,
  • HAKRA,
  • DD4,
  • C11,
  • NM_001818,
  • M33375
  • identifiers:
  • 1109,
  • ENSG00000198610,
  • AKR1C4

Genome feature

Region: gene ? Length: 22113  
Location: 10:5196835-5218947 Cyto location: 10p15.1


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Disease

1 Diseases

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Expression

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Other

142 SN Ps

5 Cross References

18 Data Sets

35 Homologues

0 Located Features

90 Rna Seq Results