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Gene : ADAMTS6 Homo sapiens

Name  ? ADAM metallopeptidase with thrombospondin type 1 motif 6 Cytological Location  5q12.3
Brief Description  ADAM metallopeptidase with thrombospondin type 1 motif 6
description  This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. Expression of this gene may be regulated by the cytokine TNF-alpha. [provided by RefSeq, Mar 2016]
  • synonyms:
  • HGNC:222,
  • NM_197941,
  • ADAMTS-6,
  • OTTHUMG00000074079,
  • uc003jtp.4,
  • ADAM-TS 6,
  • AF140674,
  • a disintegrin and metalloproteinase with thrombospondin motifs 6,
  • ADAM-TS6,
  • a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 6,
  • ADAM-TS6,
  • ADAMTS6
  • identifiers:
  • 11174,
  • ENSG00000049192,
  • ADAMTS6

Genome feature

Region: gene ? Length: 333928  
Location: 5:65148736-65482663 reverse strand Cyto location: 5q12.3


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

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Other

536 SN Ps

5 Cross References

16 Data Sets

31 Homologues

0 Located Features

90 Rna Seq Results