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Gene : KLF12 Homo sapiens

Name  ? Kruppel like factor 12 Cytological Location  13q22.1
Brief Description  Kruppel like factor 12
description  Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. The protein encoded by this gene is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • synonyms:
  • uc058xlm.1,
  • AP-2rep,
  • AP-2rep,
  • OTTHUMG00000017078,
  • AJ243274,
  • KLF12,
  • AP2REP,
  • AP-2rep transcription factor,
  • HGNC:6346,
  • NM_007249,
  • AP2REP,
  • HSPC122,
  • AP-2 repressor,
  • KLF12 zinc finger transcriptional repressor,
  • HSPC122
  • identifiers:
  • 11278,
  • ENSG00000118922,
  • KLF12

Genome feature

Region: gene ? Length: 482284  
Location: 13:73686012-74168295 reverse strand Cyto location: 13q22.1

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

193 SN Ps

5 Cross References

16 Data Sets

44 Homologues

0 Located Features

90 Rna Seq Results