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Gene : TOP1MT Homo sapiens

Name  ? DNA topoisomerase I mitochondrial Cytological Location  8q24.3
Brief Description  DNA topoisomerase I mitochondrial
description  This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
  • synonyms:
  • uc003yxz.6,
  • AF349018,
  • OTTHUMG00000164979,
  • topoisomerase (DNA) I, mitochondrial,
  • NM_052963,
  • HGNC:29787,
  • TOP1MT
  • identifiers:
  • 116447,
  • ENSG00000184428,
  • TOP1MT

Genome feature

Region: gene ? Length: 50654  
Location: 8:143309324-143359977 reverse strand Cyto location: 8q24.3


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Function

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0 Pathways

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Genomics

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Proteins

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SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Mouse Gene --> Allele [Phenotype]

Homology

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Expression

Gene(s) --> Significant SNPs (GTex data)

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Other

0 Pathways

2011 SN Ps

5 Cross References

14 Data Sets

8 Homologues

0 Located Features

90 Rna Seq Results