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Gene : ARAP2 Homo sapiens

Name  ? ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 Cytological Location  4p14
Brief Description  ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
description  The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. The protein is a phosphatidylinositol (3,4,5)-trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, but it lacks the predicted catalytic arginine in the RHO-GAP domain and does not have RHO-GAP activity. The protein associates with focal adhesions and functions downstream of RhoA to regulate focal adhesion dynamics. [provided by RefSeq, Sep 2008]
  • synonyms:
  • AF411982,
  • PARX,
  • OTTHUMG00000097811,
  • ARAP2,
  • HGNC:16924,
  • CENTD1,
  • uc003gsq.3,
  • centaurin, delta 1,
  • NM_015230,
  • CENTD1,
  • PARX
  • identifiers:
  • 116984,
  • ENSG00000047365,
  • ARAP2

Genome feature

Region: gene ? Length: 239648  
Location: 4:36005186-36244833 reverse strand Cyto location: 4p14


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Proteins

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SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

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Other

183 SN Ps

5 Cross References

17 Data Sets

7 Homologues

0 Located Features

90 Rna Seq Results