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Gene : AGAP2 Homo sapiens

Name  ? ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 Cytological Location  12q14.1
Brief Description  ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
description  The protein encoded by this gene belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase. It is overexpressed in cancer cells, and promotes cancer cell invasion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
  • synonyms:
  • CENTG1,
  • GGAP2,
  • AF413077,
  • NM_014770,
  • PIKE,
  • OTTHUMG00000170285,
  • CENTG1,
  • AGAP2,
  • HGNC:16921,
  • uc001spr.4,
  • centaurin, gamma 1
  • identifiers:
  • 116986,
  • ENSG00000135439,
  • AGAP2

Genome feature

Region: gene ? Length: 18437  
Location: 12:57723765-57742201 reverse strand Cyto location: 12q14.1


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

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Genomics

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Proteins

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SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

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Other

116 SN Ps

5 Cross References

17 Data Sets

13 Homologues

0 Located Features

90 Rna Seq Results