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Gene : TPH2 Homo sapiens

Name  ? tryptophan hydroxylase 2 Cytological Location  12q21.1
Brief Description  tryptophan hydroxylase 2
description  This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression. [provided by RefSeq, Feb 2016]
  • synonyms:
  • OTTHUMG00000169677,
  • tryptophan 5-monooxygenase,
  • NM_173353,
  • FLJ37295,
  • NTPH,
  • TPH2,
  • NTPH,
  • HGNC:20692,
  • AY098914,
  • uc009zrw.1,
  • ADHD7
  • identifiers:
  • 121278,
  • ENSG00000139287,
  • TPH2

Genome feature

Region: gene ? Length: 93596  
Location: 12:71938846-72032441 Cyto location: 12q21.1


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Function

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Gene --> GO terms.

Mouse Gene --> Allele [Phenotype]

Genomics

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

2 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

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Other

3 SN Ps

5 Cross References

17 Data Sets

8 Homologues

0 Located Features

90 Rna Seq Results