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Gene : ADH5 Homo sapiens

Name  ? alcohol dehydrogenase 5 (class III), chi polypeptide Cytological Location  4q23
Brief Description  alcohol dehydrogenase 5 (class III), chi polypeptide
description  This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene. [provided by RefSeq, Oct 2008]
  • synonyms:
  • ADHX,
  • HGNC:253,
  • ADH-3,
  • formaldehyde dehydrogenase,
  • NM_000671,
  • GSH-FDH,
  • M29872,
  • FDH,
  • ADH-3,
  • GSNOR,
  • S-nitrosoglutathione reductase,
  • FDH,
  • GSNOR,
  • ADHX,
  • HEL-S-60p,
  • ADH5,
  • OTTHUMG00000161230,
  • uc003hui.5,
  • FALDH
  • identifiers:
  • 128,
  • ENSG00000197894,
  • ADH5

Genome feature

Region: gene ? Length: 17811  
Location: 4:99070978-99088788 reverse strand Cyto location: 4q23


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Proteins

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Disease

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Homology

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Expression

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2011 SN Ps

5 Cross References

17 Data Sets

16 Homologues

0 Located Features

90 Rna Seq Results