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Gene : ATF6B Homo sapiens

Name  ? activating transcription factor 6 beta Cytological Location  6p21.32
Brief Description  activating transcription factor 6 beta
description  The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
  • synonyms:
  • uc011git.3,
  • NM_001136153,
  • HGNC:2349,
  • CREBL1,
  • G13,
  • CREBL1,
  • G13,
  • CREB-RP,
  • cAMP responsive element binding protein-like 1,
  • OTTHUMG00000031296,
  • ATF6B
  • identifiers:
  • 1388,
  • ENSG00000213676,
  • ATF6B

Genome feature

Region: gene ? Length: 12973  
Location: 6:32115268-32128240 reverse strand Cyto location: 6p21.32


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Gene -> HPO annotation (Human Phenotype Ontology)

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Genomics

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Proteins

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SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Expression

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Other

2011 SN Ps

5 Cross References

15 Data Sets

6 Homologues

0 Located Features

90 Rna Seq Results