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Gene : GAB3 Homo sapiens

Name  ? GRB2 associated binding protein 3 Cytological Location  Xq28
Brief Description  GRB2 associated binding protein 3
description  This gene is a member of the GRB2-associated binding protein gene family. These proteins are scaffolding/docking proteins that are involved in several growth factor and cytokine signaling pathways, and they contain a pleckstrin homology domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. The protein encoded by this gene facilitates macrophage differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
  • synonyms:
  • uc004fmj.3,
  • DOS/Gab family member 3,
  • AY057989,
  • GAB3,
  • NM_001081573,
  • Gab3 scaffolding protein,
  • HGNC:17515,
  • OTTHUMG00000024245
  • identifiers:
  • 139716,
  • ENSG00000160219,
  • GAB3

Genome feature

Region: gene ? Length: 76335  
Location: X:154675249-154751583 reverse strand Cyto location: Xq28

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

71 SN Ps

5 Cross References

15 Data Sets

7 Homologues

0 Located Features

90 Rna Seq Results