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Gene : GAB3 Homo sapiens

Name  ? GRB2 associated binding protein 3 Cytological Location  Xq28
Brief Description  GRB2 associated binding protein 3
description  This gene is a member of the GRB2-associated binding protein gene family. These proteins are scaffolding/docking proteins that are involved in several growth factor and cytokine signaling pathways, and they contain a pleckstrin homology domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. The protein encoded by this gene facilitates macrophage differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
  • synonyms:
  • NM_001081573,
  • Gab3 scaffolding protein,
  • OTTHUMG00000024245,
  • DOS/Gab family member 3,
  • HGNC:17515,
  • uc004fmj.3,
  • GAB3,
  • AY057989
  • identifiers:
  • 139716,
  • ENSG00000160219,
  • GAB3

Genome feature

Region: gene ? Length: 76335  
Location: X:154675249-154751583 reverse strand Cyto location: Xq28


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Function

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Genomics

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Proteins

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SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Mouse Gene --> Allele [Phenotype]

Homology

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Expression

Gene(s) --> Significant SNPs (GTex data)

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Other

0 Pathways

71 SN Ps

5 Cross References

15 Data Sets

7 Homologues

0 Located Features

90 Rna Seq Results