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Gene : ADAMTS14 Homo sapiens

Name  ? ADAM metallopeptidase with thrombospondin type 1 motif 14 Cytological Location  10q22.1
Brief Description  ADAM metallopeptidase with thrombospondin type 1 motif 14
description  This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme cleaves amino-terminal propeptides from type I procollagen, a necessary step in the formation of collagen fibers. Mutations in this gene may be associated with osteoarthritis in human patients. [provided by RefSeq, May 2016]
  • synonyms:
  • HGNC:14899,
  • AF358666,
  • OTTHUMG00000018414,
  • ADAMTS14,
  • uc001jrg.4,
  • a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 14,
  • NM_080722
  • identifiers:
  • 140766,
  • ENSG00000138316,
  • ADAMTS14

Genome feature

Region: gene ? Length: 89936  
Location: 10:70672506-70762441 Cyto location: 10q22.1


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Proteins

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SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Mouse Gene --> Allele [Phenotype]

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Expression

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Other

2011 SN Ps

4 Cross References

12 Data Sets

30 Homologues

0 Located Features

90 Rna Seq Results