help  | about  | cite  | software

Gene : TRPM6 Homo sapiens

Name  ? transient receptor potential cation channel subfamily M member 6 Cytological Location  9q21.13
Brief Description  transient receptor potential cation channel subfamily M member 6
description  This gene is predominantly expressed in the kidney and colon, and encodes a protein containing an ion channel domain and a protein kinase domain. It is crucial for magnesium homeostasis, and plays an essential role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney. Mutations in this gene are associated with hypomagnesemia with secondary hypocalcemia. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Apr 2010]
  • synonyms:
  • uc004ajl.1,
  • OTTHUMG00000020027,
  • HGNC:17995,
  • hypomagnesemia, secondary hypocalcemia,
  • CHAK2,
  • HMGX,
  • TRPM6,
  • FLJ22628,
  • CHAK2,
  • HSH,
  • HSH,
  • HOMG,
  • transient receptor potential cation channel, subfamily M, member 6,
  • HOMG,
  • HOMG1,
  • NM_017662,
  • AK026281
  • identifiers:
  • 140803,
  • ENSG00000119121,
  • TRPM6

Genome feature

Region: gene ? Length: 165600  
Location: 9:74722495-74888094 reverse strand Cyto location: 9q21.13


Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

Gene --> GO terms.

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Gene --> Orthologues

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

92 SN Ps

4 Cross References

18 Data Sets

18 Homologues

0 Located Features

90 Rna Seq Results