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Gene : ADRB2 Homo sapiens

Name  ? adrenoceptor beta 2 Cytological Location  5q32
Brief Description  adrenoceptor beta 2
description  This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq, Jul 2008]
  • synonyms:
  • ADRB2,
  • NM_000024,
  • BAR,
  • ADRB2R,
  • ADRBR,
  • OTTHUMG00000129933,
  • B2AR,
  • ADRB2R,
  • HGNC:286,
  • uc003lpr.3,
  • B2AR,
  • AF022953,
  • ADRBR,
  • adrenoceptor beta 2, surface,
  • BAR,
  • BETA2AR,
  • adrenergic, beta-2-, receptor, surface
  • identifiers:
  • 154,
  • ENSG00000169252,
  • ADRB2

Genome feature

Region: gene ? Length: 2042  
Location: 5:148826593-148828634 Cyto location: 5q32


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Genomics

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Proteins

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SNPs

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Disease

2 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

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Homology

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Expression

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Other

118 SN Ps

5 Cross References

18 Data Sets

26 Homologues

0 Located Features

90 Rna Seq Results