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Gene : AGR3 Homo sapiens

Name  ? anterior gradient 3, protein disulphide isomerase family member Cytological Location  7p21.1
Brief Description  anterior gradient 3, protein disulphide isomerase family member
description  This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This gene is expressed in ciliated airway epithelial cells and, in mouse, plays a role in ciliary beat frequency in multiciliated cells. This gene is also over-expressed in breast, ovarian, and prostrate cancers. [provided by RefSeq, Dec 2016]
  • synonyms:
  • protein disulfide isomerase family A, member 18,
  • hAG-3,
  • AGR3,
  • uc003sts.4,
  • AG-3,
  • hAG-3,
  • BCMP11,
  • AY069977,
  • OTTHUMG00000128411,
  • HAG3,
  • PDIA18,
  • BCMP11,
  • HAG3,
  • anterior gradient 3 homolog (Xenopus laevis),
  • PDIA18,
  • breast cancer membrane protein 11,
  • AG3,
  • HGNC:24167,
  • NM_176813
  • identifiers:
  • 155465,
  • ENSG00000173467,
  • AGR3

Genome feature

Region: gene ? Length: 27279  
Location: 7:16854711-16881989 reverse strand Cyto location: 7p21.1


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0 Pathways

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Disease

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Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Mouse Gene --> Allele [Phenotype]

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Expression

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0 Pathways

306 SN Ps

5 Cross References

16 Data Sets

7 Homologues

0 Located Features

90 Rna Seq Results