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Gene : AKR1C1 Homo sapiens

Name  ? aldo-keto reductase family 1 member C1 Cytological Location  10p15.1
Brief Description  aldo-keto reductase family 1 member C1
description  This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008]
  • synonyms:
  • DDH,
  • DDH1,
  • DD1,
  • OTTHUMG00000017580,
  • MBAB,
  • DD1,
  • HAKRC,
  • DDH1,
  • aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase),
  • DD1/DD2,
  • uc001ihq.4,
  • NM_001353,
  • AKR1C1,
  • HAKRC,
  • DDH,
  • HBAB,
  • 2-ALPHA-HSD,
  • C9,
  • HGNC:384,
  • H-37,
  • MBAB,
  • 20-ALPHA-HSD,
  • D26124,
  • dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase
  • identifiers:
  • 1645,
  • ENSG00000187134,
  • AKR1C1

Genome feature

Region: gene ? Length: 16706  
Location: 10:4963262-4979967 Cyto location: 10p15.1


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2011 SN Ps

5 Cross References

16 Data Sets

35 Homologues

0 Located Features

90 Rna Seq Results