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Gene : DGUOK Homo sapiens

Name  ? deoxyguanosine kinase Cytological Location  2p13.1
Brief Description  deoxyguanosine kinase
description  In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
  • synonyms:
  • NM_001318859,
  • PEOB4,
  • DGUOK,
  • U41668,
  • MTDPS3,
  • uc002sjx.3,
  • dGK,
  • dGK,
  • OTTHUMG00000129819,
  • HGNC:2858,
  • NCPH
  • identifiers:
  • 1716,
  • ENSG00000114956,
  • DGUOK

Genome feature

Region: gene ? Length: 32136  
Location: 2:73926826-73958961 Cyto location: 2p13.1


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Proteins

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SNPs

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Disease

3 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Mouse Gene --> Allele [Phenotype]

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Expression

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Other

128 SN Ps

5 Cross References

19 Data Sets

6 Homologues

0 Located Features

90 Rna Seq Results