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Gene : DPYSL2 Homo sapiens

Name  ? dihydropyrimidinase like 2 Cytological Location  8p21.2
Brief Description  dihydropyrimidinase like 2
description  This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
  • synonyms:
  • DPYSL2,
  • D78013,
  • ULIP2,
  • NM_001386,
  • CRMP-2,
  • DRP2,
  • DRP2,
  • CRMP2,
  • HGNC:3014,
  • DRP-2,
  • OTTHUMG00000099439,
  • uc003xfb.3,
  • dihydropyrimidinase-like 2,
  • DHPRP2,
  • DHPRP2,
  • ULIP-2,
  • DRP-2,
  • CRMP2,
  • N2A3
  • identifiers:
  • 1808,
  • ENSG00000092964,
  • DPYSL2

Genome feature

Region: gene ? Length: 143985  
Location: 8:26514193-26658177 Cyto location: 8p21.2

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Gene -> HPO annotation (Human Phenotype Ontology)

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



805 SN Ps

5 Cross References

18 Data Sets

8 Homologues

0 Located Features

90 Rna Seq Results