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Gene : AGTR1 Homo sapiens

Name  ? angiotensin II receptor type 1 Cytological Location  3q24
Brief Description  angiotensin II receptor type 1
description  Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene. [provided by RefSeq, Jul 2012]
  • synonyms:
  • AT1B,
  • OTTHUMG00000159503,
  • AT1R,
  • angiotensin receptor 1B,
  • AT2R1B,
  • AT2R1,
  • AG2S,
  • HGNC:336,
  • AGTR1B,
  • AGTR1A,
  • AG2S,
  • AT1AR,
  • AT2R1A,
  • AT2R1,
  • AT1,
  • AGTR1,
  • AGTR1B,
  • NM_000685,
  • AT1,
  • M87290,
  • HAT1R,
  • HAT1R,
  • AT1B,
  • AT1BR,
  • uc003ewj.4
  • identifiers:
  • 185,
  • ENSG00000144891,
  • AGTR1

Genome feature

Region: gene ? Length: 45133  
Location: 3:148697871-148743003 Cyto location: 3q24


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SNPs

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Disease

2 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Expression

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Other

379 SN Ps

5 Cross References

19 Data Sets

23 Homologues

0 Located Features

90 Rna Seq Results