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Gene : APOBEC3A Homo sapiens

Name  ? apolipoprotein B mRNA editing enzyme catalytic subunit 3A Cytological Location  22q13.1
Brief Description  apolipoprotein B mRNA editing enzyme catalytic subunit 3A
description  This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene lacks the zinc binding activity of other family members. The protein plays a role in immunity, by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines, which leads to DNA degradation. However, other mechanisms are also thought to be involved, as anti-viral effect is not dependent on deaminase activity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012]
  • synonyms:
  • PHRBN,
  • APOBEC3A,
  • PHRBN,
  • uc011aoc.3,
  • HGNC:17343,
  • phorbolin I,
  • A3A,
  • apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A,
  • OTTHUMG00000151004,
  • NM_145699,
  • bK150C2.1,
  • ARP3,
  • ARP3,
  • U03891
  • identifiers:
  • 200315,
  • ENSG00000128383,
  • APOBEC3A

Genome feature

Region: gene ? Length: 5662  
Location: 22:38957522-38963183 Cyto location: 22q13.1


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Proteins

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SNPs

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Disease

0 Diseases

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Homology

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Expression

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Other

58 SN Ps

5 Cross References

16 Data Sets

10 Homologues

0 Located Features

90 Rna Seq Results