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Gene : AKT2 Homo sapiens

Name  ? AKT serine/threonine kinase 2 Cytological Location  19q13.2
Brief Description  AKT serine/threonine kinase 2
description  This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. [provided by RefSeq, Jul 2008]
  • synonyms:
  • PRKBB,
  • uc002onf.3,
  • HIHGHH,
  • v-akt murine thymoma viral oncogene homolog 2,
  • RAC-BETA,
  • AKT2,
  • PKBBETA,
  • M77198,
  • HGNC:392,
  • NM_001626,
  • PKBB,
  • OTTHUMG00000137375
  • identifiers:
  • 208,
  • ENSG00000105221,
  • AKT2

Genome feature

Region: gene ? Length: 55215  
Location: 19:40230317-40285531 reverse strand Cyto location: 19q13.2


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Function

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119 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

2 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Gene --> Orthologues

Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

119 Pathways

37 SN Ps

5 Cross References

20 Data Sets

39 Homologues

0 Located Features

90 Rna Seq Results