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Gene : ALDH3A1 Homo sapiens

Name  ? aldehyde dehydrogenase 3 family member A1 Cytological Location  17p11.2
Brief Description  aldehyde dehydrogenase 3 family member A1
description  Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008]
  • synonyms:
  • OTTHUMG00000059469,
  • uc002gwj.4,
  • ALDH3,
  • M74542,
  • ALDH3A1,
  • aldehyde dehydrogenase 3 family, member A1,
  • ALDHIII,
  • ALDH3,
  • aldehyde dehydrogenase, dimeric NADP-preferring,
  • HGNC:405,
  • NM_000691
  • identifiers:
  • 218,
  • ENSG00000108602,
  • ALDH3A1

Genome feature

Region: gene ? Length: 10450  
Location: 17:19737984-19748433 reverse strand Cyto location: 17p11.2


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SNPs

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Disease

0 Diseases

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Expression

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Other

280 SN Ps

5 Cross References

17 Data Sets

11 Homologues

0 Located Features

90 Rna Seq Results