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Gene : ACSL4 Homo sapiens

Name  ? acyl-CoA synthetase long chain family member 4 Cytological Location  Xq23
Brief Description  acyl-CoA synthetase long chain family member 4
description  The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the cognitive disability or Alport syndrome. Alternative splicing of this gene generates multiple transcript variants. [provided by RefSeq, Jan 2016]
  • synonyms:
  • fatty-acid-Coenzyme A ligase, long-chain 4,
  • MRX68,
  • ACS4,
  • FACL4,
  • uc004eoi.3,
  • LACS4,
  • ACSL4,
  • long-chain fatty-acid-Coenzyme A ligase 4,
  • MRX68,
  • OTTHUMG00000022190,
  • NM_004458,
  • BC034959,
  • lignoceroyl-CoA synthase,
  • mental retardation, X-linked 68,
  • MRX63,
  • LACS4,
  • ACS4,
  • FACL4,
  • HGNC:3571,
  • MRX63,
  • mental retardation, X-linked 63
  • identifiers:
  • 2182,
  • ENSG00000068366,
  • ACSL4

Genome feature

Region: gene ? Length: 92074  
Location: X:109641330-109733403 reverse strand Cyto location: Xq23


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Disease

1 Diseases

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91 SN Ps

5 Cross References

19 Data Sets

13 Homologues

0 Located Features

90 Rna Seq Results