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Gene : AAK1 Homo sapiens

Name  ? AP2 associated kinase 1 Cytological Location  2p13.3
Brief Description  AP2 associated kinase 1
description  Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
  • synonyms:
  • KIAA1048,
  • uc002sfp.3,
  • AB028971,
  • DKFZp686K16132,
  • HGNC:19679,
  • OTTHUMG00000129648,
  • AAK1,
  • NM_014911
  • identifiers:
  • 22848,
  • ENSG00000115977,
  • AAK1

Genome feature

Region: gene ? Length: 185851  
Location: 2:69457995-69643845 reverse strand Cyto location: 2p13.3


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Proteins

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SNPs

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Disease

0 Diseases

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Homology

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Expression

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Other

345 SN Ps

5 Cross References

16 Data Sets

11 Homologues

0 Located Features

90 Rna Seq Results