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Gene : ARL2BP Homo sapiens

Name  ? ADP ribosylation factor like GTPase 2 binding protein Cytological Location  16q13
Brief Description  ADP ribosylation factor like GTPase 2 binding protein
description  ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. The protein encoded by this gene binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of this protein or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. This protein is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTPase-activating protein activity. [provided by RefSeq, Jul 2008]
  • synonyms:
  • HGNC:17146,
  • BART1,
  • NM_012106,
  • ADP-ribosylation factor-like 2 binding protein,
  • uc002elf.2,
  • RP66,
  • BART1,
  • retinitis pigmentosa 66 (autosomal recessive),
  • RP66,
  • ARL2BP,
  • binder of Arl2,
  • AF126062,
  • BART,
  • BART,
  • OTTHUMG00000133459
  • identifiers:
  • 23568,
  • ENSG00000102931,
  • ARL2BP

Genome feature

Region: gene ? Length: 8508  
Location: 16:57245126-57253633 Cyto location: 16q13


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Proteins

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SNPs

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Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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Expression

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Other

29 SN Ps

5 Cross References

18 Data Sets

3 Homologues

0 Located Features

90 Rna Seq Results