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Gene : AKR7L Homo sapiens

Name  ? aldo-keto reductase family 7 like (gene/pseudogene) Cytological Location  1p36.13|1p35-p36.1
Brief Description  aldo-keto reductase family 7 like (gene/pseudogene)
description  This gene is one of three aldo-keto reductase genes that are present in a cluster on the p arm of chromosome 1. The encoded proteins are involved in the reduction of the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. It has been speculated that this family member encodes a selenoprotein, which includes a selenocysteine (Sec) residue in lieu of a UGA translational termination codon. However, there is no evidence that such a protein is produced in vivo. The alternative interpretation is that this family member is a segregating pseudogene, where some individuals have an allele that encodes a functional enzyme, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Feb 2017]
  • synonyms:
  • HGNC:24056,
  • AFAR3,
  • uc057cwi.1,
  • AFB1-AR 3,
  • AFB1-AR3,
  • OTTHUMG00000002520,
  • AKR7L,
  • AKR7A4,
  • AFAR3,
  • NM_201252,
  • aldo-keto reductase family 7-like
  • identifiers:
  • 246181,
  • ENSG00000211454,
  • AKR7L

Genome feature

Region: gene ? Length: 14849  
Location: 1:19259320-19274168 reverse strand Cyto location: 1p36.13|1p35-p36.1


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Disease

0 Diseases

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796 SN Ps

5 Cross References

12 Data Sets

4 Homologues

0 Located Features

53 Rna Seq Results