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Gene : SPDEF Homo sapiens

Name  ? SAM pointed domain containing ETS transcription factor Cytological Location  6p21.31
Brief Description  SAM pointed domain containing ETS transcription factor
description  The protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells, and functions as an androgen-independent transactivator of prostate-specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain, breast, lung and ovarian tumors, compared to the corresponding normal tissues, and it shows better tumor-association than other cancer-associated molecules, making it a more suitable target for developing specific cancer therapies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
  • synonyms:
  • OTTHUMG00000014548,
  • AF071538,
  • bA375E1.3,
  • SPDEF,
  • SAM pointed domain containing ets transcription factor,
  • PDEF,
  • NM_012391,
  • HGNC:17257,
  • uc003ojq.3,
  • bA375E1.3,
  • PDEF
  • identifiers:
  • 25803,
  • ENSG00000124664,
  • SPDEF

Genome feature

Region: gene ? Length: 18534  
Location: 6:34537800-34556333 reverse strand Cyto location: 6p21.31


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0 Pathways

17 SN Ps

5 Cross References

15 Data Sets

32 Homologues

0 Located Features

90 Rna Seq Results