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Gene : ARFGAP3 Homo sapiens

Name  ? ADP ribosylation factor GTPase activating protein 3 Cytological Location  22q13.2
Brief Description  ADP ribosylation factor GTPase activating protein 3
description  The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene. [provided by RefSeq, Nov 2008]
  • synonyms:
  • uc003bdd.3,
  • HGNC:661,
  • AK002083,
  • ADP-ribosylation factor GTPase activating protein 1,
  • ARFGAP1,
  • NM_014570,
  • ARFGAP3,
  • OTTHUMG00000150718,
  • ARFGAP1
  • identifiers:
  • 26286,
  • ENSG00000242247,
  • ARFGAP3

Genome feature

Region: gene ? Length: 60877  
Location: 22:42796526-42857402 reverse strand Cyto location: 22q13.2


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Disease

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Expression

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2011 SN Ps

5 Cross References

16 Data Sets

7 Homologues

0 Located Features

90 Rna Seq Results