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Gene : GGT1 Homo sapiens

Name  ? gamma-glutamyltransferase 1 Cytological Location  22q11.23
Brief Description  gamma-glutamyltransferase 1
description  The enzyme encoded by this gene is a type I gamma-glutamyltransferase that catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. The enzyme is composed of a heavy chain and a light chain, which are derived from a single precursor protein. It is expressed in tissues involved in absorption and secretion and may contribute to the etiology of diabetes and other metabolic disorders. Multiple alternatively spliced variants have been identified. There are a number of related genes present on chromosomes 20 and 22, and putative pseudogenes for this gene on chromosomes 2, 13, and 22. [provided by RefSeq, Jan 2014]
  • synonyms:
  • GGT,
  • GTG,
  • D22S672,
  • CD224,
  • D22S732,
  • GGTD,
  • HGNC:4250,
  • uc003aan.2,
  • D22S672,
  • NM_013430,
  • CD224,
  • D22S732,
  • OTTHUMG00000030859,
  • GGT1,
  • GGT 1,
  • M24903,
  • GGT
  • identifiers:
  • 2678,
  • ENSG00000100031,
  • GGT1

Genome feature

Region: gene ? Length: 45256  
Location: 22:24583750-24629005 Cyto location: 22q11.23

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Orthologues


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



743 SN Ps

6 Cross References

17 Data Sets

21 Homologues

0 Located Features

90 Rna Seq Results