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Gene : ABL2 Homo sapiens

Name  ? ABL proto-oncogene 2, non-receptor tyrosine kinase Cytological Location  1q25.2
Brief Description  ABL proto-oncogene 2, non-receptor tyrosine kinase
description  This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2009]
  • synonyms:
  • uc001gmj.5,
  • ABLL,
  • HGNC:77,
  • c-abl oncogene 2, non-receptor tyrosine kinase,
  • ABL2,
  • NM_005158,
  • ABLL,
  • ARG,
  • M14904,
  • v-abl Abelson murine leukemia viral oncogene homolog 2,
  • ARG,
  • v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene),
  • OTTHUMG00000035199,
  • Abelson-related gene
  • identifiers:
  • 27,
  • ENSG00000143322,
  • ABL2

Genome feature

Region: gene ? Length: 130367  
Location: 1:179099327-179229693 reverse strand Cyto location: 1q25.2


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2011 SN Ps

5 Cross References

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90 Rna Seq Results