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Gene : DISC1 Homo sapiens

Name  ? DISC1 scaffold protein Cytological Location  1q42.2
Brief Description  disrupted in schizophrenia 1
description  This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  • synonyms:
  • OTTHUMG00000037835,
  • AF222980,
  • SCZD9,
  • NM_018662,
  • uc010pww.3,
  • HGNC:2888,
  • DISC1,
  • disrupted in schizophrenia 1,
  • C1orf136
  • identifiers:
  • 27185,
  • ENSG00000162946,
  • DISC1

Genome feature

Region: gene ? Length: 414458  
Location: 1:231626815-232041272 Cyto location: 1q42.2


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Function

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0 Pathways

Gene --> GO terms.

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Mouse Gene --> Allele [Phenotype]

Homology

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Gene --> Orthologues

Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

0 Pathways

2011 SN Ps

5 Cross References

16 Data Sets

3 Homologues

0 Located Features

90 Rna Seq Results