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Gene : SLCO1B3 Homo sapiens

Name  ? solute carrier organic anion transporter family member 1B3 Cytological Location  12p12.2
Brief Description  solute carrier organic anion transporter family member 1B3
description  This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of endogenous and xenobiotic compounds and plays a critical role in bile acid and bilirubin transport. Mutations in this gene are a cause of Rotor type hyperbilirubinemia. Alternative splicing of this gene and the use of alternative promoters results in transcript variants encoding different isoforms that differ in their tissue specificity. [provided by RefSeq, Mar 2017]
  • synonyms:
  • SLC21A8,
  • solute carrier family 21 (organic anion transporter), member 8,
  • SLC21A8,
  • LST-2,
  • LST3,
  • HBLRR,
  • OATP1B3,
  • OATP8,
  • OATP-8,
  • LST-3TM13,
  • NM_019844,
  • SLCO1B3,
  • solute carrier organic anion transporter family, member 1B3,
  • OATP8,
  • OATP1B3,
  • uc001rel.5,
  • HGNC:10961,
  • OTTHUMG00000169011
  • identifiers:
  • 28234,
  • ENSG00000111700,
  • SLCO1B3

Genome feature

Region: gene ? Length: 106208  
Location: 12:20810704-20916911 Cyto location: 12p12.2


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Disease

1 Diseases

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Expression

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Other

2011 SN Ps

4 Cross References

17 Data Sets

21 Homologues

0 Located Features

90 Rna Seq Results