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Gene : ANG Homo sapiens

Name  ? angiogenin Cytological Location  14q11.2
Brief Description  angiogenin
description  The protein encoded by this gene is an exceedingly potent mediator of new blood vessel formation. It hydrolyzes cellular tRNAs resulting in decreased protein synthesis and is similar to pancreatic ribonuclease. In addition, the mature peptide has antimicrobial activity against some bacteria and fungi, including S. pneumoniae and C. albicans. Alternative splicing results in two transcript variants encoding the same protein. This gene and the gene that encodes ribonuclease, RNase A family, 4 share promoters and 5' exons. Each gene splices to a unique downstream exon that contains its complete coding region. [provided by RefSeq, Aug 2014]
  • synonyms:
  • angiogenin, ribonuclease, RNase A family, 5,
  • uc001vxw.4,
  • ALS9,
  • RNASE5,
  • HGNC:483,
  • ribonuclease A family member 5,
  • ANG,
  • OTTHUMG00000029576,
  • NM_001097577,
  • RNASE4,
  • RNASE5,
  • RAA1,
  • RAA1,
  • HEL168
  • identifiers:
  • 283,
  • ENSG00000214274,
  • ANG

Genome feature

Region: gene ? Length: 10010  
Location: 14:20684177-20694186 Cyto location: 14q11.2


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Proteins

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SNPs

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Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

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Homology

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Expression

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Other

91 SN Ps

5 Cross References

17 Data Sets

22 Homologues

0 Located Features

90 Rna Seq Results