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Gene : GRPR Homo sapiens

Name  ? gastrin releasing peptide receptor Cytological Location  Xp22.2
Brief Description  gastrin releasing peptide receptor
description  Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene. [provided by RefSeq, Jul 2008]
  • synonyms:
  • BB2R,
  • NM_005314,
  • OTTHUMG00000021189,
  • bombesin receptor 2,
  • BB2,
  • uc004cxj.4,
  • BB2R,
  • BB2,
  • HGNC:4609,
  • GRPR
  • identifiers:
  • 2925,
  • ENSG00000126010,
  • GRPR

Genome feature

Region: gene ? Length: 30218  
Location: X:16123301-16153518 Cyto location: Xp22.2


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Proteins

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SNPs

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Disease

0 Diseases

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Expression

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Other

63 SN Ps

5 Cross References

14 Data Sets

14 Homologues

0 Located Features

90 Rna Seq Results