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Gene : VPREB3 Homo sapiens

Name  ? V-set pre-B cell surrogate light chain 3 Cytological Location  22q11.23|22q11
Brief Description  V-set pre-B cell surrogate light chain 3
description  The protein encoded by this gene is the human ortholog of the mouse VpreB3 (8HS20) protein, is thought to be involved in B-cell maturation, and may play a role in assembly of the pre-B cell receptor (pre-BCR). While the role of this protein in B-cell development has not yet been elucidated, studies with the chicken ortholog of this protein have found that when overexpressed, this protein localizes to the endoplasmic reticulum. The mouse ortholog of this protein has been shown to associate with membrane mu heavy chains early in the course of pre-B cell receptor biosynthesis. Expression of this gene has been observed in some lymphomas. [provided by RefSeq, Apr 2015]
  • synonyms:
  • HGNC:12710,
  • 8HS20,
  • VPREB3,
  • 8HS20,
  • OTTHUMG00000150738,
  • pre-B lymphocyte 3,
  • NM_013378,
  • uc002zxt.4,
  • N27C7-2
  • identifiers:
  • 29802,
  • ENSG00000128218,
  • VPREB3

Genome feature

Region: gene ? Length: 1701  
Location: 22:23752743-23754443 reverse strand Cyto location: 22q11.23|22q11


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Proteins

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Disease

0 Diseases

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Mouse Gene --> Allele [Phenotype]

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Expression

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2011 SN Ps

5 Cross References

13 Data Sets

106 Homologues

0 Located Features

90 Rna Seq Results