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Gene : ANAPC4 Homo sapiens

Name  ? anaphase promoting complex subunit 4 Cytological Location  4p15.2
Brief Description  anaphase promoting complex subunit 4
description  A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The exact function of this gene product is not known. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
  • synonyms:
  • ANAPC4,
  • OTTHUMG00000097753,
  • HGNC:19990,
  • APC4,
  • NM_013367,
  • AF191338,
  • uc003gro.4,
  • APC4
  • identifiers:
  • 29945,
  • ENSG00000053900,
  • ANAPC4

Genome feature

Region: gene ? Length: 41273  
Location: 4:25377226-25418498 Cyto location: 4p15.2


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Function

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41 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

41 Pathways

2011 SN Ps

5 Cross References

16 Data Sets

6 Homologues

0 Located Features

90 Rna Seq Results