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Gene : GZMH Homo sapiens

Name  ? granzyme H Cytological Location  14q12
Brief Description  granzyme H
description  This gene encodes a member of the peptidase S1 family of serine proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a chymotrypsin-like protease. This protein is reported to be constitutively expressed in the NK (natural killer) cells of the immune system and may play a role in the cytotoxic arm of the innate immune response by inducing target cell death and by directly cleaving substrates in pathogen-infected cells. This gene is present in a gene cluster with another member of the granzyme subfamily on chromosome 14. [provided by RefSeq, Nov 2015]
  • synonyms:
  • CTSGL2,
  • uc001wpr.3,
  • cathepsin G-like 2, protein h-CCPX,
  • CSP-C,
  • NM_033423,
  • CGL-2,
  • OTTHUMG00000140185,
  • CCP-X,
  • CGL-2,
  • granzyme H (cathepsin G-like 2, protein h-CCPX),
  • CSP-C,
  • CTLA1,
  • HGNC:4710,
  • CCP-X,
  • GZMH,
  • CTLA1,
  • M72150,
  • CTSGL2
  • identifiers:
  • 2999,
  • ENSG00000100450,
  • GZMH

Genome feature

Region: gene ? Length: 3284  
Location: 14:24606480-24609763 reverse strand Cyto location: 14q12

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0 Diseases

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7 SN Ps

5 Cross References

15 Data Sets

73 Homologues

0 Located Features

90 Rna Seq Results