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Gene : H2AFX Homo sapiens

Name  ? H2A histone family member X Cytological Location  11q23.3
Brief Description  H2A histone family member X
description  Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015]
  • synonyms:
  • HGNC:4739,
  • NM_002105,
  • H2AX,
  • H2A histone family, member X,
  • uc001pvg.4,
  • OTTHUMG00000166196,
  • H2AX,
  • H2AFX,
  • X14850,
  • H2A.X,
  • H2A/X
  • identifiers:
  • 3014,
  • ENSG00000188486,
  • H2AFX

Genome feature

Region: gene ? Length: 1594  
Location: 11:119093874-119095467 reverse strand Cyto location: 11q23.3

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83 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Orthologues


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



83 Pathways

6 SN Ps

5 Cross References

17 Data Sets

24 Homologues

5 Located Features

90 Rna Seq Results