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Gene : HBG2 Homo sapiens

Name  ? hemoglobin subunit gamma 2 Cytological Location  11p15.4
Brief Description  hemoglobin subunit gamma 2
description  The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'- epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008]
  • synonyms:
  • OTTHUMG00000066673,
  • HBG-T1,
  • hemoglobin, gamma G,
  • NM_000184,
  • HGNC:4832,
  • HBG-T1,
  • uc001mak.2,
  • TNCY,
  • HBG2,
  • BC029387
  • identifiers:
  • 3048,
  • ENSG00000196565,
  • HBG2

Genome feature

Region: gene ? Length: 1591  
Location: 11:5253191-5254781 reverse strand Cyto location: 11p15.4


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Function

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

2 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Gene --> Orthologues

Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

212 SN Ps

5 Cross References

17 Data Sets

19 Homologues

0 Located Features

90 Rna Seq Results