help  | about  | cite  | software

Gene : NRG1 Homo sapiens

Name  ? neuregulin 1 Cytological Location  8p12
Brief Description  neuregulin 1
description  The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD). [provided by RefSeq, Apr 2016]
  • synonyms:
  • NDF,
  • NRG1,
  • GGF,
  • NRG1-IT2,
  • MST131,
  • HRG,
  • MSTP131,
  • NM_001159995,
  • L12261,
  • HGL,
  • GGF2,
  • NDF,
  • SMDF,
  • uc064luk.1,
  • NRG1-IT2,
  • HRGA,
  • HRG,
  • ARIA,
  • OTTHUMG00000163918,
  • HGNC:7997,
  • NRG1 intronic transcript 2 (non-protein coding),
  • GGF,
  • HGL,
  • HRG1
  • identifiers:
  • 3084,
  • ENSG00000157168,
  • NRG1

Genome feature

Region: gene ? Length: 1132495  
Location: 8:31639222-32771716 Cyto location: 8p12


Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

Gene --> GO terms.

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Gene --> Orthologues

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

835 SN Ps

5 Cross References

19 Data Sets

7 Homologues

0 Located Features

90 Rna Seq Results