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Gene : ACACA Homo sapiens

Name  ? acetyl-CoA carboxylase alpha Cytological Location  17q12
Brief Description  acetyl-CoA carboxylase alpha
description  Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • synonyms:
  • ACAC,
  • ACACAD,
  • ACCA,
  • HGNC:84,
  • NM_198836,
  • ACC,
  • U19822,
  • ACC1,
  • OTTHUMG00000188463,
  • uc284osy.1,
  • ACC,
  • ACC1,
  • ACAC,
  • acetyl-CoA carboxylase 1,
  • acetyl-Coenzyme A carboxylase alpha,
  • ACACA
  • identifiers:
  • 31,
  • ENSG00000278540,
  • ACACA

Genome feature

Region: gene ? Length: 321831  
Location: 17:37084992-37406822 reverse strand Cyto location: 17q12


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Disease

1 Diseases

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0 SN Ps

5 Cross References

16 Data Sets

9 Homologues

0 Located Features

37 Rna Seq Results