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Gene : HLA-G Homo sapiens

Name  ? major histocompatibility complex, class I, G Cytological Location  6p22.1
Brief Description  major histocompatibility complex, class I, G
description  HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail. [provided by RefSeq, Jul 2008]
  • synonyms:
  • b2 microglobulin,
  • NM_002127,
  • uc003nnw.2,
  • OTTHUMG00000031157,
  • MHC-G,
  • HLA-G histocompatibility antigen, class I, G,
  • HGNC:4964,
  • HLA-G
  • identifiers:
  • 3135,
  • ENSG00000204632,
  • HLA-G

Genome feature

Region: gene ? Length: 4164  
Location: 6:29826967-29831130 Cyto location: 6p22.1

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1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



24236 SN Ps

5 Cross References

16 Data Sets

95 Homologues

0 Located Features

90 Rna Seq Results