help  | about  | cite  | software

Gene : AOC2 Homo sapiens

Name  ? amine oxidase copper containing 2 Cytological Location  17q21.31
Brief Description  amine oxidase, copper containing 2
description  Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
  • synonyms:
  • uc002ibu.5,
  • AOC2,
  • HGNC:549,
  • DAO2,
  • NM_001158,
  • OTTHUMG00000180655,
  • AF081363,
  • DAO2,
  • NM_009590,
  • SSAO,
  • amine oxidase, copper containing 2 (retina-specific),
  • RAO,
  • RAO
  • identifiers:
  • 314,
  • ENSG00000131480,
  • AOC2

Genome feature

Region: gene ? Length: 6130  
Location: 17:42844583-42850712 Cyto location: 17q21.31


Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Gene --> Orthologues

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

13 SN Ps

5 Cross References

15 Data Sets

4 Homologues

0 Located Features

90 Rna Seq Results