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Gene : TLX1 Homo sapiens

Name  ? T cell leukemia homeobox 1 Cytological Location  10q24.31
Brief Description  T cell leukemia homeobox 1
description  This gene encodes a nuclear transcription factor that belongs to the NK-linked or NK-like (NKL) subfamily of homeobox genes. The encoded protein is required for normal development of the spleen during embryogenesis. This protein is also involved in specification of neuronal cell fates. Ectopic expression of this gene due to chromosomal translocations is associated with certain T-cell acute lymphoblastic leukemias. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010]
  • synonyms:
  • M62626,
  • HOX11,
  • HOX11,
  • T-cell leukemia homeobox 1,
  • NM_005521,
  • HGNC:5056,
  • TCL3,
  • homeo box 11 (T-cell lymphoma 3-associated breakpoint),
  • uc001ksw.4,
  • Homeo box-11 (T-cell leukemia-3 associated breakpoint, homologous to Drosophila Notch),
  • OTTHUMG00000019341,
  • TCL3,
  • T-cell leukemia, homeobox 1,
  • TLX1
  • identifiers:
  • 3195,
  • ENSG00000107807,
  • TLX1

Genome feature

Region: gene ? Length: 7017  
Location: 10:101130773-101137789 Cyto location: 10q24.31


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Proteins

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SNPs

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Disease

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Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Mouse Gene --> Allele [Phenotype]

Homology

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Expression

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0 Pathways

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5 Cross References

13 Data Sets

6 Homologues

0 Located Features

90 Rna Seq Results