help  | about  | cite  | software

Gene : TLX1 Homo sapiens

Name  ? T cell leukemia homeobox 1 Cytological Location  10q24.31
Brief Description  T cell leukemia homeobox 1
description  This gene encodes a nuclear transcription factor that belongs to the NK-linked or NK-like (NKL) subfamily of homeobox genes. The encoded protein is required for normal development of the spleen during embryogenesis. This protein is also involved in specification of neuronal cell fates. Ectopic expression of this gene due to chromosomal translocations is associated with certain T-cell acute lymphoblastic leukemias. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010]
  • synonyms:
  • HOX11,
  • Homeo box-11 (T-cell leukemia-3 associated breakpoint, homologous to Drosophila Notch),
  • TLX1,
  • T-cell leukemia, homeobox 1,
  • OTTHUMG00000019341,
  • TCL3,
  • TCL3,
  • homeo box 11 (T-cell lymphoma 3-associated breakpoint),
  • NM_005521,
  • T-cell leukemia homeobox 1,
  • HGNC:5056,
  • M62626,
  • HOX11,
  • uc001ksw.4
  • identifiers:
  • 3195,
  • ENSG00000107807,
  • TLX1

Genome feature

Region: gene ? Length: 7017  
Location: 10:101130773-101137789 Cyto location: 10q24.31

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer

Gene --> Orthologues


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

0 SN Ps

5 Cross References

13 Data Sets

6 Homologues

0 Located Features

90 Rna Seq Results